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Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases
FYCO1 is a multidomain adaptor protein that plays an important role in autophagy by mediating the kinesin-dependent microtubule plus-end-directed transport of autophagosomes. FYCO1 contains a RUN domain, which is hypothesized to function as a specific effector for members of the Ras superfamily of s...
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| Publicado no: | Acta Crystallogr F Struct Biol Commun |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397462/ https://ncbi.nlm.nih.gov/pubmed/32744243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20009012 |
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