The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation

SHC adaptor protein (SHCA) and lipoma-preferred partner (LPP) mediate transforming growth factor β (TGFβ)-induced breast cancer cell migration and invasion. Reduced expression of either protein diminishes breast cancer lung metastasis, but the reason for this effect is unclear. Here, using total int...

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Udgivet i:J Biol Chem
Main Authors: Kiepas, Alex, Voorand, Elena, Senecal, Julien, Ahn, Ryuhjin, Annis, Matthew G., Jacquet, Kévin, Tali, George, Bisson, Nicolas, Ursini-Siegel, Josie, Siegel, Peter M., Brown, Claire M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397114/
https://ncbi.nlm.nih.gov/pubmed/32299913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011903
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