p66ShcA functions as a contextual promoter of breast cancer metastasis

BACKGROUND: The p66ShcA redox protein is the longest isoform of the Shc1 gene and is variably expressed in breast cancers. In response to a variety of stress stimuli, p66ShcA becomes phosphorylated on serine 36, which allows it to translocate from the cytoplasm to the mitochondria where it stimulate...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Breast Cancer Res
Glavni autori: Lewis, Kyle, Kiepas, Alex, Hudson, Jesse, Senecal, Julien, Ha, Jacqueline R., Voorand, Elena, Annis, Matthew G., Sabourin, Valerie, Ahn, Ryuhjin, La Selva, Rachel, Tabariès, Sébastien, Hsu, Brian E., Siegel, Matthew J., Dankner, Matthew, Canedo, Eduardo Cepeda, Lajoie, Mathieu, Watson, Ian R., Brown, Claire M., Siegel, Peter M., Ursini-Siegel, Josie
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964019/
https://ncbi.nlm.nih.gov/pubmed/31941526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-1245-6
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items