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p66ShcA functions as a contextual promoter of breast cancer metastasis
BACKGROUND: The p66ShcA redox protein is the longest isoform of the Shc1 gene and is variably expressed in breast cancers. In response to a variety of stress stimuli, p66ShcA becomes phosphorylated on serine 36, which allows it to translocate from the cytoplasm to the mitochondria where it stimulate...
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| Izdano u: | Breast Cancer Res |
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| Glavni autori: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6964019/ https://ncbi.nlm.nih.gov/pubmed/31941526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-1245-6 |
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