CobT and BzaC catalyze the regiospecific activation and methylation of the 5-hydroxybenzimidazole lower ligand in anaerobic cobamide biosynthesis

Vitamin B(12) and other cobamides are essential cofactors required by many organisms and are synthesized by a subset of prokaryotes via distinct aerobic and anaerobic routes. The anaerobic biosynthesis of 5,6-dimethylbenzimidazole (DMB), the lower ligand of vitamin B(12), involves five reactions cat...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Mathur, Yamini, Sreyas, Sheryl, Datar, Prathamesh M., Sathian, Manjima B., Hazra, Amrita B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Editors' Picks
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397103/
https://ncbi.nlm.nih.gov/pubmed/32503839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014197
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky