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Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica
BACKGROUND: Cobamide diversity arises from the nature of the nucleotide base. Nicotinate mononucleotide (NaMN):base phosphoribosyltransferases (CobT) synthesize α-linked riboside monophosphates from diverse nucleotide base substrates (e.g., benzimidazoles, purines, and phenolics) that are incorporat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900240/ https://ncbi.nlm.nih.gov/pubmed/24121107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.09.038 |
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