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Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica

BACKGROUND: Cobamide diversity arises from the nature of the nucleotide base. Nicotinate mononucleotide (NaMN):base phosphoribosyltransferases (CobT) synthesize α-linked riboside monophosphates from diverse nucleotide base substrates (e.g., benzimidazoles, purines, and phenolics) that are incorporat...

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Détails bibliographiques
Auteurs principaux: Chan, Chi Ho, Newmister, Sean A., Talyor, Keenan, Claas, Kathy R., Rayment, Ivan, Escalante-Semerena, Jorge C.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900240/
https://ncbi.nlm.nih.gov/pubmed/24121107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.09.038
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