Functional Analysis of the Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase (CobT) Enzyme, Involved in the Late Steps of Coenzyme B(12) Biosynthesis in Salmonella enterica

Eitemau Tebyg

• The cobT gene of Salmonella typhimurium encodes the NaMN: 5,6-dimethylbenzimidazole phosphoribosyltransferase responsible for the synthesis of N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole, an intermediate in the synthesis of the nucleotide loop of cobalamin.
  gan: Trzebiatowski, J R, et al.
  Cyhoeddwyd: (1994)
• Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica
  gan: Chan, Chi Ho, et al.
  Cyhoeddwyd: (2013)
• Reduction of Cob(III)alamin to Cob(II)alamin in Salmonella enterica Serovar Typhimurium LT2
  gan: Fonseca, Maris V., et al.
  Cyhoeddwyd: (2000)
• The end of the cob operon: evidence that the last gene (cobT) catalyzes synthesis of the lower ligand of vitamin B12, dimethylbenzimidazole.
  gan: Chen, P, et al.
  Cyhoeddwyd: (1995)
• Biologically Active Isoforms of CobB Sirtuin Deacetylase in Salmonella enterica and Erwinia amylovora
  gan: Tucker, Alex C., et al.
  Cyhoeddwyd: (2010)