Mycobacterium paratuberculosis CobT Activates Dendritic Cells via Engagement of Toll-like Receptor 4 Resulting in Th1 Cell Expansion

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne disease in animals and MAP involvement in human Crohn disease has been recently emphasized. Evidence from M. tuberculosis studies suggests mycobacterial proteins activate dendritic cells (DCs) via Toll-like receptor (T...

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Detalhes bibliográficos
Main Authors: Byun, Eui-Hong, Kim, Woo Sik, Kim, Jong-Seok, Won, Choul-Jae, Choi, Han-Gyu, Kim, Hwa-Jung, Cho, Sang-Nae, Lee, Keehoon, Zhang, Tiejun, Hur, Gang Min, Shin, Sung Jae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493906/
https://ncbi.nlm.nih.gov/pubmed/23019321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.391060
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