Mycobacterium paratuberculosis CobT Activates Dendritic Cells via Engagement of Toll-like Receptor 4 Resulting in Th1 Cell Expansion

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne disease in animals and MAP involvement in human Crohn disease has been recently emphasized. Evidence from M. tuberculosis studies suggests mycobacterial proteins activate dendritic cells (DCs) via Toll-like receptor (T...

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Dettagli Bibliografici
Autori principali: Byun, Eui-Hong, Kim, Woo Sik, Kim, Jong-Seok, Won, Choul-Jae, Choi, Han-Gyu, Kim, Hwa-Jung, Cho, Sang-Nae, Lee, Keehoon, Zhang, Tiejun, Hur, Gang Min, Shin, Sung Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493906/
https://ncbi.nlm.nih.gov/pubmed/23019321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.391060
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