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Rewriting history: Epigenetic reprogramming of CD8(+) T cell differentiation to enhance immunotherapy
The full potential of T cell-based immunotherapies remains limited by a variety of T cell extrinsic and intrinsic immunosuppressive mechanisms that can become imprinted to stably reduce the antitumor ability of T cells. Here we discuss recent insights into memory CD8(+) T cell differentiation and ex...
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| Опубликовано в: : | Trends Immunol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7395868/ https://ncbi.nlm.nih.gov/pubmed/32624330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2020.06.008 |
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