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Rewriting history: Epigenetic reprogramming of CD8(+) T cell differentiation to enhance immunotherapy

The full potential of T cell-based immunotherapies remains limited by a variety of T cell extrinsic and intrinsic immunosuppressive mechanisms that can become imprinted to stably reduce the antitumor ability of T cells. Here we discuss recent insights into memory CD8(+) T cell differentiation and ex...

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書目詳細資料
發表在:Trends Immunol
Main Authors: Zebley, Caitlin C., Gottschalk, Stephen, Youngblood, Ben
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395868/
https://ncbi.nlm.nih.gov/pubmed/32624330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2020.06.008
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