Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis

Antigen-independent homeostasis of memory CD8 T cells is vital for sustaining long-lived T cell–mediated immunity. In this study, we report that maintenance of human memory CD8 T cell effector potential during in vitro and in vivo homeostatic proliferation is coupled to preservation of acquired DNA...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Exp Med
Hlavní autoři: Abdelsamed, Hossam A., Moustaki, Ardiana, Fan, Yiping, Dogra, Pranay, Ghoneim, Hazem E., Zebley, Caitlin C., Triplett, Brandon M., Sekaly, Rafick-Pierre, Youngblood, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461005/
https://ncbi.nlm.nih.gov/pubmed/28490440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161760
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky