Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis

Antigen-independent homeostasis of memory CD8 T cells is vital for sustaining long-lived T cell–mediated immunity. In this study, we report that maintenance of human memory CD8 T cell effector potential during in vitro and in vivo homeostatic proliferation is coupled to preservation of acquired DNA...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Abdelsamed, Hossam A., Moustaki, Ardiana, Fan, Yiping, Dogra, Pranay, Ghoneim, Hazem E., Zebley, Caitlin C., Triplett, Brandon M., Sekaly, Rafick-Pierre, Youngblood, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461005/
https://ncbi.nlm.nih.gov/pubmed/28490440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161760
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