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Liquid-liquid phase separation and its mechanistic role in pathological protein aggregation

Liquid-liquid phase separation (LLPS) of proteins underlies the formation of membrane-less organelles. While it has been recognized for some time that these organelles are of key importance for normal cellular functions, a growing number of recent observations indicates that LLPS may also play a rol...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Babinchak, W. Michael, Surewicz, Witold K.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395662/
https://ncbi.nlm.nih.gov/pubmed/32169484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.03.004
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