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Vitamin K-dependent carboxylation of coagulation factors: insights from a cell-based functional study

Vitamin K-dependent carboxylation is a post-translational modification essential for the biological function of coagulation factors. Defects in carboxylation are mainly associated with bleeding disorders. With the discovery of new vitamin K-dependent proteins, the importance of carboxylation now enc...

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Dettagli Bibliografici
Pubblicato in:Haematologica
Autori principali: Hao, Zhenyu, Jin, Da-Yun, Stafford, Darrel W., Tie, Jian-Ke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395276/
https://ncbi.nlm.nih.gov/pubmed/31624106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.229047
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