A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells

Aberrantly expressed cytokines in the bone marrow (BM) niche are increasingly recognized as critical mediators of survival and expansion of leukemic stem cells. To identify regulators of primitive chronic myeloid leukemia (CML) cells, we performed a high-content cytokine screen using primary CD34(+)...

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Publicado no:Haematologica
Main Authors: von Palffy, Sofia, Landberg, Niklas, Sandén, Carl, Zacharaki, Dimitra, Shah, Mansi, Nakamichi, Naoto, Hansen, Nils, Askmyr, Maria, Lilljebjörn, Henrik, Rissler, Marianne, Karlsson, Christine, Scheding, Stefan, Richter, Johan, Eaves, Connie J., Bhatia, Ravi, Järås, Marcus, Fioretos, Thoas
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395258/
https://ncbi.nlm.nih.gov/pubmed/31582541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.220434
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