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New Inhibitors for the BPTF Bromodomain Enabled by Structural Biology and Biophysical Assay Development
Bromodomain-containing proteins regulate transcription through protein-protein interactions with chromatin and serve as scaffolding proteins for recruiting essential members of the transcriptional machinery. One such protein is the bromodomain and PHD-containing transcription factor (BPTF), the larg...
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| Pubblicato in: | Org Biomol Chem |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7393680/ https://ncbi.nlm.nih.gov/pubmed/32588860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob00506a |
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