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Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor
Bromodomain and PHD finger containing protein transcription factor (BPTF) is an epigenetic protein involved in chromatin remodelling and is a potential anticancer target. The BPTF bromodomain has one reported small molecule inhibitor (AU1, rac-1). Here, advances made on the structure-activity relati...
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| 出版年: | Org Biomol Chem |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374164/ https://ncbi.nlm.nih.gov/pubmed/30706071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02599a |
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