New Inhibitors for the BPTF Bromodomain Enabled by Structural Biology and Biophysical Assay Development

Bromodomain-containing proteins regulate transcription through protein-protein interactions with chromatin and serve as scaffolding proteins for recruiting essential members of the transcriptional machinery. One such protein is the bromodomain and PHD-containing transcription factor (BPTF), the larg...

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Detaylı Bibliyografya
Yayımlandı:Org Biomol Chem
Asıl Yazarlar: Ycas, Peter D., Zahid, Huda, Chan, Alice, Olson, Noelle M., Johnson, Jorden A., Talluri, Siva K., Schonbrunn, Ernst, Pomerantz, William C. K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393680/
https://ncbi.nlm.nih.gov/pubmed/32588860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob00506a
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