Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases

Bacteria are known to evade β-lactam antibiotic action by producing β-lactamases (BLs), including carbapenemases, which are able to hydrolyze nearly all available β-lactams. The production of BLs represents one of the best known and most targeted mechanisms of resistance in bacteria. We have perform...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Spyrakis, Francesca, Santucci, Matteo, Maso, Lorenzo, Cross, Simon, Gianquinto, Eleonora, Sannio, Filomena, Verdirosa, Federica, De Luca, Filomena, Docquier, Jean-Denis, Cendron, Laura, Tondi, Donatella, Venturelli, Alberto, Cruciani, Gabriele, Costi, Maria Paola
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391774/
https://ncbi.nlm.nih.gov/pubmed/32728062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69431-y
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items