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Platelet α-granules are required for occlusive high-shear-rate thrombosis

von Willebrand factor (VWF) is essential for the induction of arterial thrombosis. In this study, we investigated the critical role of platelet VWF in occlusive thrombosis formation at high shear in mice that do not express platelet VWF (Nbeal2(−/−)). Using in silico modeling, in vitro high-shear mi...

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Publicat a:Blood Adv
Autors principals: Kim, Dongjune A., Ashworth, Katrina J., Di Paola, Jorge, Ku, David N.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391145/
https://ncbi.nlm.nih.gov/pubmed/32697818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002117
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