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Platelet α-granules are required for occlusive high-shear-rate thrombosis
von Willebrand factor (VWF) is essential for the induction of arterial thrombosis. In this study, we investigated the critical role of platelet VWF in occlusive thrombosis formation at high shear in mice that do not express platelet VWF (Nbeal2(−/−)). Using in silico modeling, in vitro high-shear mi...
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| Publié dans: | Blood Adv |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7391145/ https://ncbi.nlm.nih.gov/pubmed/32697818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002117 |
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