P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Adenosine triphosphate (ATP) and its metabolite, adenosine, are key regulators of polymorphonuclear neutrophil (PMN) functions. PMNs have recently been implicated in the initiation of thrombosis. We investigated the role of ATP and adenosine in PMN activation and recruitment at the site of endotheli...

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Detalhes bibliográficos
Main Authors: Darbousset, Roxane, Delierneux, Céline, Mezouar, Soraya, Hego, Alexandre, Lecut, Christelle, Guillaumat, Isabelle, Riederer, Markus A., Evans, Richard J., Dignat-George, Françoise, Panicot-Dubois, Laurence, Oury, Cécile, Dubois, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199960/
https://ncbi.nlm.nih.gov/pubmed/25150292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571679
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