P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Adenosine triphosphate (ATP) and its metabolite, adenosine, are key regulators of polymorphonuclear neutrophil (PMN) functions. PMNs have recently been implicated in the initiation of thrombosis. We investigated the role of ATP and adenosine in PMN activation and recruitment at the site of endotheli...

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Bibliographic Details
Main Authors: Darbousset, Roxane, Delierneux, Céline, Mezouar, Soraya, Hego, Alexandre, Lecut, Christelle, Guillaumat, Isabelle, Riederer, Markus A., Evans, Richard J., Dignat-George, Françoise, Panicot-Dubois, Laurence, Oury, Cécile, Dubois, Christophe
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2014
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199960/
https://ncbi.nlm.nih.gov/pubmed/25150292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571679
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