P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Adenosine triphosphate (ATP) and its metabolite, adenosine, are key regulators of polymorphonuclear neutrophil (PMN) functions. PMNs have recently been implicated in the initiation of thrombosis. We investigated the role of ATP and adenosine in PMN activation and recruitment at the site of endotheli...

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Autors principals: Darbousset, Roxane, Delierneux, Céline, Mezouar, Soraya, Hego, Alexandre, Lecut, Christelle, Guillaumat, Isabelle, Riederer, Markus A., Evans, Richard J., Dignat-George, Françoise, Panicot-Dubois, Laurence, Oury, Cécile, Dubois, Christophe
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199960/
https://ncbi.nlm.nih.gov/pubmed/25150292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571679
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