P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Adenosine triphosphate (ATP) and its metabolite, adenosine, are key regulators of polymorphonuclear neutrophil (PMN) functions. PMNs have recently been implicated in the initiation of thrombosis. We investigated the role of ATP and adenosine in PMN activation and recruitment at the site of endotheli...

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Hlavní autoři: Darbousset, Roxane, Delierneux, Céline, Mezouar, Soraya, Hego, Alexandre, Lecut, Christelle, Guillaumat, Isabelle, Riederer, Markus A., Evans, Richard J., Dignat-George, Françoise, Panicot-Dubois, Laurence, Oury, Cécile, Dubois, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199960/
https://ncbi.nlm.nih.gov/pubmed/25150292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571679
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