P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Adenosine triphosphate (ATP) and its metabolite, adenosine, are key regulators of polymorphonuclear neutrophil (PMN) functions. PMNs have recently been implicated in the initiation of thrombosis. We investigated the role of ATP and adenosine in PMN activation and recruitment at the site of endotheli...

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Autori principali: Darbousset, Roxane, Delierneux, Céline, Mezouar, Soraya, Hego, Alexandre, Lecut, Christelle, Guillaumat, Isabelle, Riederer, Markus A., Evans, Richard J., Dignat-George, Françoise, Panicot-Dubois, Laurence, Oury, Cécile, Dubois, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2014
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199960/
https://ncbi.nlm.nih.gov/pubmed/25150292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-571679
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