Role of lncRNA Morrbid in PTPN11(Shp2)(E76K)-driven juvenile myelomonocytic leukemia

Mutations in PTPN11, which encodes the protein tyrosine phosphatase SHP2, contribute to ∼35% of cases of juvenile myelomonocytic leukemia (JMML). A common clinical picture in children with JMML is that it presents as a constitutive hyperinflammatory syndrome, partially reminiscent of chronic myelomo...

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Bibliografiska uppgifter
I publikationen:Blood Adv
Huvudupphovsmän: Cai, Zhigang, Zhang, Chi, Kotzin, Jonathan J., Williams, Adam, Henao-Mejia, Jorge, Kapur, Reuben
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2020
Ämnen:
Myeloid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391141/
https://ncbi.nlm.nih.gov/pubmed/32697817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002123
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