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Role of lncRNA Morrbid in PTPN11(Shp2)(E76K)-driven juvenile myelomonocytic leukemia
Mutations in PTPN11, which encodes the protein tyrosine phosphatase SHP2, contribute to ∼35% of cases of juvenile myelomonocytic leukemia (JMML). A common clinical picture in children with JMML is that it presents as a constitutive hyperinflammatory syndrome, partially reminiscent of chronic myelomo...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7391141/ https://ncbi.nlm.nih.gov/pubmed/32697817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002123 |
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