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STIM1 controls calcineurin/Akt/mTOR/NFATC2-mediated osteoclastogenesis induced by RANKL/M-CSF

Store-operated Ca(2+) entry (SOCE) is the stable calcium channel influx in most cells. It consists of the cytoplasmic ion channel ORAI and endoplasmic reticulum receptor stromal interaction molecule 1 (STIM1). Abolition of SOCE function due to ORAI1 and STIM1 gene defects may cause non-perspiration,...

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Publicado en:Exp Ther Med
Autores principales: Huang, Yanjiao, Li, Qiang, Feng, Zunyong, Zheng, Lanrong
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388407/
https://ncbi.nlm.nih.gov/pubmed/32742319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8774
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