No relation between docetaxel administration route and high‐grade diarrhea incidence

Oral administration of docetaxel in combination with the CYP3A4 inhibitor ritonavir is used in clinical trials to improve oral bioavailability of docetaxel. Diarrhea was the most commonly observed and dose‐limiting toxicity. This study combined preclinical and clinical data and investigated incidenc...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Hendrikx, Jeroen J. M. A., Stuurman, Frederik E., Song, Ji‐Ying, de Weger, Vincent A., Lagas, Jurjen S., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H., Schellens, Jan H. M., Marchetti, Serena
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387127/
https://ncbi.nlm.nih.gov/pubmed/32725720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.633
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