No relation between docetaxel administration route and high‐grade diarrhea incidence

Oral administration of docetaxel in combination with the CYP3A4 inhibitor ritonavir is used in clinical trials to improve oral bioavailability of docetaxel. Diarrhea was the most commonly observed and dose‐limiting toxicity. This study combined preclinical and clinical data and investigated incidenc...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Hendrikx, Jeroen J. M. A., Stuurman, Frederik E., Song, Ji‐Ying, de Weger, Vincent A., Lagas, Jurjen S., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H., Schellens, Jan H. M., Marchetti, Serena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387127/
https://ncbi.nlm.nih.gov/pubmed/32725720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.633
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