Age-specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1-polarization

Due to functionally distinct cell-mediated immunity, newborns and infants are highly susceptible to infection with intracellular pathogens. Indeed, neonatal antigen-presenting dendritic cells (DCs) demonstrate impaired Th1 responses to many candidate adjuvants, including most TLR agonists (TLRAs). C...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: van Haren, Simon D., Dowling, David J., Foppen, Willemina, Christensen, Dennis, Andersen, Peter, Reed, Steven G., Hershberg, Robert M., Baden, Lindsey R, Levy, Ofer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386828/
https://ncbi.nlm.nih.gov/pubmed/27793997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600282
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller