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NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease

Thiopurine has been used to maintain remission and to reduce antidrug antibody formation in monoclonal antibody therapy in patients with inflammatory bowel disease (IBD). The use of thiopurine is limited by side effects such as leukopenia. Thiopurine S-methyltransferase (TPMT) variants are associate...

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Detalhes bibliográficos
Publicado no:Intest Res
Autor principal: Matsuoka, Katsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Association for the Study of Intestinal Diseases 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385579/
https://ncbi.nlm.nih.gov/pubmed/32482022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5217/ir.2020.00002
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