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Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients
BACKGROUND: Genetic variants of TPMT and NUDT15 have been reported to predict the inter-patient variability in response and toxicity profiles of patients receiving thiopurine therapy. However, the clinical utility of TPMT genotyping in guiding thiopurine doses has been questionable, in part due to u...
Shranjeno v:
| izdano v: | Pharmacogenomics |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Future Medicine Ltd
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5753614/ https://ncbi.nlm.nih.gov/pubmed/29210335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0147 |
| Oznake: |
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