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Homologous repair deficiency score for identifying breast cancers with defective DNA damage response
Breast cancer (BC) in patients with germline mutations of BRCA1/BRCA2 are associated with benefit from drugs targeting DNA damage response (DDR), but they account for only 5–7% of overall breast cancer. To define the characteristics of these tumors and also to identify tumors without BRCA mutation b...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385153/ https://ncbi.nlm.nih.gov/pubmed/32719318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68176-y |
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