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Perturbation biology links temporal protein changes to drug responses in a melanoma cell line

Cancer cells have genetic alterations that often directly affect intracellular protein signaling processes allowing them to bypass control mechanisms for cell death, growth and division. Cancer drugs targeting these alterations often work initially, but resistance is common. Combinations of targeted...

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Bibliografski detalji
Izdano u:PLoS Comput Biol
Glavni autori: Nyman, Elin, Stein, Richard R., Jing, Xiaohong, Wang, Weiqing, Marks, Benjamin, Zervantonakis, Ioannis K., Korkut, Anil, Gauthier, Nicholas P., Sander, Chris
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384681/
https://ncbi.nlm.nih.gov/pubmed/32667922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007909
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