An Updated Organ-Based Multi-Level Model for Glucose Homeostasis: Organ Distributions, Timing, and Impact of Blood Flow

le Herrgårdh, Tilda, Li, Hao, Nyman, Elin, Cedersund, Gunnar
Foilsithe in Front Physiol (2021)

A systems biology analysis connects insulin receptor signaling with glucose transporter translocation in rat adipocytes

le Bergqvist, Niclas, Nyman, Elin, Cedersund, Gunnar, Stenkula, Karin G.
Foilsithe in J Biol Chem (2017)

Cross-talks via mTORC2 can explain enhanced activation in response to insulin in diabetic patients

le Magnusson, Rasmus, Gustafsson, Mika, Cedersund, Gunnar, Strålfors, Peter, Nyman, Elin
Foilsithe in Biosci Rep (2017)

Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes

le Rajan, Meenu Rohini, Nyman, Elin, Kjølhede, Preben, Cedersund, Gunnar, Strålfors, Peter
Foilsithe in J Biol Chem (2016)

A Single Mechanism Can Explain Network-wide Insulin Resistance in Adipocytes from Obese Patients with Type 2 Diabetes

le Nyman, Elin, Rajan, Meenu Rohini, Fagerholm, Siri, Brännmark, Cecilia, Cedersund, Gunnar, Strålfors, Peter
Foilsithe in J Biol Chem (2014)

A Hierarchical Whole-body Modeling Approach Elucidates the Link between in Vitro Insulin Signaling and in Vivo Glucose Homeostasis

le Nyman, Elin, Brännmark, Cecilia, Palmér, Robert, Brugård, Jan, Nyström, Fredrik H., Strålfors, Peter, Cedersund, Gunnar
Foilsithe 2011

Insulin Signaling in Type 2 Diabetes: EXPERIMENTAL AND MODELING ANALYSES REVEAL MECHANISMS OF INSULIN RESISTANCE IN HUMAN ADIPOCYTES

le Brännmark, Cecilia, Nyman, Elin, Fagerholm, Siri, Bergenholm, Linnéa, Ekstrand, Eva-Maria, Cedersund, Gunnar, Strålfors, Peter
Foilsithe 2013

Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes

le Nyman, Elin, Bartesaghi, Stefano, Melin Rydfalk, Rebecka, Eng, Sandra, Pollard, Charlotte, Gennemark, Peter, Peng, Xiao-Rong, Cedersund, Gunnar
Foilsithe in NPJ Syst Biol Appl (2017)

Mechanisms of a Sustained Anti‐inflammatory Drug Response in Alveolar Macrophages Unraveled with Mathematical Modeling

le Nyman, Elin, Lindh, Maria, Lövfors, William, Simonsson, Christian, Persson, Alexander, Eklund, Daniel, Bäckström, Erica, Fridén, Markus, Cedersund, Gunnar
Foilsithe in CPT Pharmacometrics Syst Pharmacol (2020)

Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State

le Sips, Fianne L. P., Nyman, Elin, Adiels, Martin, Hilbers, Peter A. J., Strålfors, Peter, van Riel, Natal A. W., Cedersund, Gunnar
Foilsithe in PLoS One (2015)

Mathematical modeling of white adipocyte exocytosis predicts adiponectin secretion and quantifies the rates of vesicle exo- and endocytosis

le Brännmark, Cecilia, Lövfors, William, Komai, Ali M., Axelsson, Tom, El Hachmane, Mickaël F., Musovic, Saliha, Paul, Alexandra, Nyman, Elin, Olofsson, Charlotta S.
Foilsithe in J Biol Chem (2017)

Perturbation biology links temporal protein changes to drug responses in a melanoma cell line

le Nyman, Elin, Stein, Richard R., Jing, Xiaohong, Wang, Weiqing, Marks, Benjamin, Zervantonakis, Ioannis K., Korkut, Anil, Gauthier, Nicholas P., Sander, Chris
Foilsithe in PLoS Comput Biol (2020)

Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes

le Nyman, Elin, Rozendaal, Yvonne J. W., Helmlinger, Gabriel, Hamrén, Bengt, Kjellsson, Maria C., Strålfors, Peter, van Riel, Natal A. W., Gennemark, Peter, Cedersund, Gunnar
Foilsithe in Interface Focus (2016)

LASSIM—A network inference toolbox for genome-wide mechanistic modeling

le Magnusson, Rasmus, Mariotti, Guido Pio, Köpsén, Mattias, Lövfors, William, Gawel, Danuta R., Jörnsten, Rebecka, Linde, Jörg, Nordling, Torbjörn E. M., Nyman, Elin, Schulze, Sylvie, Nestor, Colm E., Zhang, Huan, Cedersund, Gunnar, Benson, Mikael, Tjärnberg, Andreas, Gustafsson, Mika
Foilsithe in PLoS Comput Biol (2017)