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Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes

Insulin resistance is a major aspect of type 2 diabetes (T2D), which results from impaired insulin signaling in target cells. Signaling to regulate forkhead box protein O1 (FOXO1) may be the most important mechanism for insulin to control transcription. Despite this, little is known about how insuli...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Rajan, Meenu Rohini, Nyman, Elin, Kjølhede, Preben, Cedersund, Gunnar, Strålfors, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957062/
https://ncbi.nlm.nih.gov/pubmed/27226562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715763
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