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Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes

Insulin resistance is a major aspect of type 2 diabetes (T2D), which results from impaired insulin signaling in target cells. Signaling to regulate forkhead box protein O1 (FOXO1) may be the most important mechanism for insulin to control transcription. Despite this, little is known about how insuli...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rajan, Meenu Rohini, Nyman, Elin, Kjølhede, Preben, Cedersund, Gunnar, Strålfors, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957062/
https://ncbi.nlm.nih.gov/pubmed/27226562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715763
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