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Phosphorylation of IRS1 at Serine 307 in Response to Insulin in Human Adipocytes Is Not Likely to be Catalyzed by p70 Ribosomal S6 Kinase

The insulin receptor substrate-1 (IRS1) is phosphorylated on serine 307 (human sequence, corresponding to murine serine 302) in response to insulin as part of a feedback loop that controls IRS1 phosphorylation on tyrosine residues by the insulin receptor. This in turn directly affects downstream sig...

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Bibliografiska uppgifter
Huvudupphovsmän: Rajan, Meenu Rohini, Fagerholm, Siri, Jönsson, Cecilia, Kjølhede, Preben, Turkina, Maria V., Strålfors, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614923/
https://ncbi.nlm.nih.gov/pubmed/23565163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059725
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