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Amides as Bioisosteres of Triazole-Based Geranylgeranyl Diphosphate Synthase Inhibitors
Geranylgeranyl diphosphate synthase (GGDPS) inhibitors are of potential therapeutic interest as a consequence of their activity against the bone marrow cancer multiple myeloma. A series of bisphosphonates linked to an isoprenoid tail through an amide linkage has been prepared and tested for the abil...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384665/ https://ncbi.nlm.nih.gov/pubmed/32690260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115604 |
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