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Directed evolution methods for overcoming trade-offs between protein activity and stability
Engineered proteins are being widely developed and employed in applications ranging from enzyme catalysts to therapeutic antibodies. Directed evolution, an iterative experimental process composed of mutagenesis and library screening, is a powerful technique for enhancing existing protein activities...
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| Udgivet i: | AIChE J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384606/ https://ncbi.nlm.nih.gov/pubmed/32719568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/aic.16814 |
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