Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity

Obesity is characterized by adipose tissue inflammation. Because proteoglycans regulate inflammation, here we investigate their role in adipose tissue inflammation in obesity. We find that adipose tissue versican and biglycan increase in obesity. Versican is produced mainly by adipocytes and biglyca...

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Foilsithe in:Cell Rep
Main Authors: Han, Chang Yeop, Kang, Inkyung, Harten, Ingrid A., Gebe, John A., Chan, Christina K., Omer, Mohamed, Alonge, Kimberly M., den Hartigh, Laura J., Kjerulf, Diego Gomes, Goodspeed, Leela, Subramanian, Savitha, Wang, Shari, Kim, Francis, Birk, David E., Wight, Thomas N., Chait, Alan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384517/
https://ncbi.nlm.nih.gov/pubmed/32610121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107818
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