Adipocyte-specific deficiency of NADPH oxidase 4 delays the onset of insulin resistance and attenuates adipose tissue inflammation in obesity

OBJECTIVE: Obesity is associated with insulin resistance and adipose tissue inflammation. Reactive oxygen species (ROS) increase in adipose tissue during the development of obesity. We previously showed that in response to excess nutrients like glucose and palmitate, adipocytes generated ROS via NAD...

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Detaylı Bibliyografya
Yayımlandı:Arterioscler Thromb Vasc Biol
Asıl Yazarlar: Den Hartigh, Laura J., Omer, Mohamed, Goodspeed, Leela, Wang, Shari, Wietecha, Tomasz, O’Brien, Kevin D., Han, Chang Yeop
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323321/
https://ncbi.nlm.nih.gov/pubmed/28062496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308749
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