Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice

BACKGROUND: Widely used as a weight loss supplement, trans-10,cis-12 conjugated linoleic acid (10,12 CLA) promotes fat loss in obese mice and humans, but has also been associated with insulin resistance. OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restr...

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Veröffentlicht in:PLoS One
Hauptverfasser: den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Wietecha, Tomasz, Houston, Barbara, Omer, Mohamed, Ogimoto, Kayoko, Subramanian, Savitha, Gowda, G. A. Nagana, O’Brien, Kevin D., Kaiyala, Karl J., Morton, Gregory J., Chait, Alan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330530/
https://ncbi.nlm.nih.gov/pubmed/28245284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172912
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