Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice

BACKGROUND: Widely used as a weight loss supplement, trans-10,cis-12 conjugated linoleic acid (10,12 CLA) promotes fat loss in obese mice and humans, but has also been associated with insulin resistance. OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restr...

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Pubblicato in:PLoS One
Autori principali: den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Wietecha, Tomasz, Houston, Barbara, Omer, Mohamed, Ogimoto, Kayoko, Subramanian, Savitha, Gowda, G. A. Nagana, O’Brien, Kevin D., Kaiyala, Karl J., Morton, Gregory J., Chait, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330530/
https://ncbi.nlm.nih.gov/pubmed/28245284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172912
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