Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice

BACKGROUND: Widely used as a weight loss supplement, trans-10,cis-12 conjugated linoleic acid (10,12 CLA) promotes fat loss in obese mice and humans, but has also been associated with insulin resistance. OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restr...

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Опубликовано в: :PLoS One
Главные авторы: den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Wietecha, Tomasz, Houston, Barbara, Omer, Mohamed, Ogimoto, Kayoko, Subramanian, Savitha, Gowda, G. A. Nagana, O’Brien, Kevin D., Kaiyala, Karl J., Morton, Gregory J., Chait, Alan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330530/
https://ncbi.nlm.nih.gov/pubmed/28245284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172912
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