Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice

BACKGROUND: Widely used as a weight loss supplement, trans-10,cis-12 conjugated linoleic acid (10,12 CLA) promotes fat loss in obese mice and humans, but has also been associated with insulin resistance. OBJECTIVE: We therefore sought to directly compare weight loss by 10,12 CLA versus caloric restr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Wietecha, Tomasz, Houston, Barbara, Omer, Mohamed, Ogimoto, Kayoko, Subramanian, Savitha, Gowda, G. A. Nagana, O’Brien, Kevin D., Kaiyala, Karl J., Morton, Gregory J., Chait, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330530/
https://ncbi.nlm.nih.gov/pubmed/28245284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172912
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