Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages

Pathogenic microorganisms are sensed by the inflammasome, resulting in the release of the pro-immune and proinflammatory cytokine interleukin-1β (IL-1β). In humans, the paired <underline>s</underline>ialic acid-binding Ig-like lectin receptors Siglec-5 (inhibitory) and Siglec-14 (activat...

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Publicat a:J Innate Immun
Autors principals: Tsai, Chih-Ming, Riestra, Angelica M., Ali, Syed Raza, Fong, Jerry J., Liu, Janet Z., Hughes, Gillian, Varki, Ajit, Nizet, Victor
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383293/
https://ncbi.nlm.nih.gov/pubmed/31805552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000504323
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