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Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells

Natural killer (NK) cells are innate immune lymphocytes that recognize and destroy abnormal host cells, such as tumor cells or those infected by viral pathogens. To safely accomplish these functions, NK cells display activating receptors that detect stress molecules or viral ligands displayed at the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fong, Jerry J., Tsai, Chih-Ming, Saha, Sudeshna, Nizet, Victor, Varki, Ajit, Bui, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187154/
https://ncbi.nlm.nih.gov/pubmed/30254166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804108115
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