Group A Streptococcal M Protein Activates the NLRP3 Inflammasome

Group A Streptococcus (GAS) is among the top 10 causes of infection-related mortality in humans. M protein is the most abundant GAS surface protein, and M1 serotype GAS strains are associated with invasive infections including necrotizing fasciitis and toxic shock syndrome. Here we report that relea...

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Publicado en:Nat Microbiol
Main Authors: Valderrama, J. Andrés, Riestra, Angelica M., Gao, Nina J., LaRock, Christopher N., Gupta, Naveen, Ali, Syed Raza, Hoffman, Hal M., Ghosh, Partho, Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750061/
https://ncbi.nlm.nih.gov/pubmed/28784982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0005-6
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