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Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing
The antimicrobial peptide LL-37 is generated upon proteolytic cleavage of cathelicidin and limits invading pathogens by directly targeting microbial membranes as well as stimulating innate immune cell function. However, some microbes evade LL-37-mediated defense. Notably, Group A Streptococcus (GAS)...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Host Microbe |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636435/ https://ncbi.nlm.nih.gov/pubmed/26468750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.09.004 |
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