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Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

Histones are essential elements of chromatin structure and gene regulation in eukaryotes. An unexpected attribute of these nuclear proteins is their antimicrobial activity. A framework for histone release and function in host defense in vivo was revealed with the discovery of neutrophil extracellula...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Döhrmann, Simon, LaRock, Christopher N., Anderson, Ericka L., Cole, Jason N., Ryali, Brinda, Stewart, Chelsea, Nonejuie, Poochit, Pogliano, Joe, Corriden, Ross, Ghosh, Partho, Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318940/
https://ncbi.nlm.nih.gov/pubmed/28220899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43039
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