Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

Histones are essential elements of chromatin structure and gene regulation in eukaryotes. An unexpected attribute of these nuclear proteins is their antimicrobial activity. A framework for histone release and function in host defense in vivo was revealed with the discovery of neutrophil extracellula...

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Udgivet i:Sci Rep
Main Authors: Döhrmann, Simon, LaRock, Christopher N., Anderson, Ericka L., Cole, Jason N., Ryali, Brinda, Stewart, Chelsea, Nonejuie, Poochit, Pogliano, Joe, Corriden, Ross, Ghosh, Partho, Nizet, Victor
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318940/
https://ncbi.nlm.nih.gov/pubmed/28220899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43039
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