2390. Avibactam Sensitizes NDM Klebsiella pneumoniae to Innate Immune Killing by Human Cathelicidin LL-37, Serum, Neutrophils, and Platelets

BACKGROUND: Avibactam (AVI) is a broad-spectrum intravenous non-β-lactam/β-lactamase inhibitor with no reported activity against metallo-β-lactamases such as New Delhi metallo-β-lactamases (NDM). Structural similarities between β-lactamases and bacterial penicillin-binding proteins (PBPs) have led i...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Open Forum Infect Dis
Huvudupphovsmän: Ulloa, Erlinda Rose, Dillon, Nicholas, Sakoulas, George, Nizet, Victor
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255312/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.2043
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk