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2390. Avibactam Sensitizes NDM Klebsiella pneumoniae to Innate Immune Killing by Human Cathelicidin LL-37, Serum, Neutrophils, and Platelets
BACKGROUND: Avibactam (AVI) is a broad-spectrum intravenous non-β-lactam/β-lactamase inhibitor with no reported activity against metallo-β-lactamases such as New Delhi metallo-β-lactamases (NDM). Structural similarities between β-lactamases and bacterial penicillin-binding proteins (PBPs) have led i...
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| Vydáno v: | Open Forum Infect Dis |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6255312/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.2043 |
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