Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing

The antimicrobial peptide LL-37 is generated upon proteolytic cleavage of cathelicidin and limits invading pathogens by directly targeting microbial membranes as well as stimulating innate immune cell function. However, some microbes evade LL-37-mediated defense. Notably, Group A Streptococcus (GAS)...

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Bibliografski detalji
Izdano u:Cell Host Microbe
Glavni autori: LaRock, Christopher N., Döhrmann, Simon, Todd, Jordan, Corriden, Ross, Olson, Joshua, Johannssen, Timo, Lepenies, Bernd, Gallo, Richard L., Ghosh, Partho, Nizet, Victor
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636435/
https://ncbi.nlm.nih.gov/pubmed/26468750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.09.004
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