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A natural missing link between activated and downhill protein folding scenarios

We propose protein PTB1:4W as a good candidate for engineering into a downhill folder. PTB1:4W has a probe-dependent thermal unfolding curve and sub-millisecond T-jump relaxation kinetics on more than one time scale. Its refolding rate in denaturant is a nonlinear function of denaturant concentratio...

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Bibliografske podrobnosti
izdano v:Phys Chem Chem Phys
Main Authors: Liu, Feng, Maynard, Caroline, Scott, Gregory, Melnykov, Artem, Hall, Kathleen B., Gruebele, Martin
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382783/
https://ncbi.nlm.nih.gov/pubmed/20336253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b925033f
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